Services
Since 1972, DavosPharma has serviced the pharmaceutical industry, from preclinical to commercial. Over the years, the company has established an excellent reputation in evaluating, coordinating and delivering drug development through our strategic partners. Today, DavosPharma offers a comprehensive, fully integrated global development and manufacturing service model.
DavosPharma’s Global Development and Manufacturing Platform utilizes the single, best capabilities that any particular CRO/CMO has to offer. Our proprietary network of CRO/CMO partners provides a fully integrated development and manufacturing capability that is tailored to the client's specific needs.
DavosPharma’s Global Discovery and Manufacturing Platforms operate in both small molecule and biological therapeutics with established FDA-inspected partners worldwide.
In order to provide a comprehensive, fully integrated CMC platform, DavosPharma has developed expertise in purification, analytical method development, pre-formulation and formulation development, encompassing solid oral dosage, sterile and non-sterile liquids, topical and high potency and cytoxic drug substances.
Discovery
- Lead and hit identification and optimization
- Discovery Chemistry
- Molecular Modeling
- Pharmacology
- Efficacy Studies
- ADME
- Safety Studies
Development
- Program directed medicinal chemistry
- Route scouting and scale up
- Pre-formulation with in vitro and in vivo assessment (Spray dried despersions, etc.)
- Full range of DMPK and Toxicolgy study capabilities, including long term Toxicology
- Stability
- Complete analytical and bio-analytical capabilities
- IND CMC support
- Program Management
- Process optimization and industrialization
Clinical and Commercial GMP Manufacturing
- API's, Intermediates and regulated starting materials --Non-Potent, Cytotoxic, HPAPI
- Spray Drying (aqueous or organic solvents)
- Drug Products -Oral solid dosage forms, Topical, Sterile
- Stability
- Import/Export
- Program Management